Sometimes the things that irritate the body can be the most helpful. At least this is the case with the active component of chili pepper. An irritant to many animals, including humans, the capsaicin component causes peppers to have a “spicy” flavor (Mason, 2004). This aspect of chili pepper causes an excitation of neurons and increases sensitivity, which causes itching and burning sensations (Mason, 2004). These sensations are the pepper's defense mechanisms to protect it from being eaten by other species. So how could something that creates an instant negative response in the body be positive? When extracted and used with a unique method, capsaicin that creates a burning sensation can actually bring a better sensation. Capsaicin can be used for medical purposes. Three studies show that capsaicin can be used to treat chronic pain, restore cardiac autonomic functions, and maintain modest body weight loss. However, there is also a deeper effect of these studies that stands out. In a study conducted by Lorna Mason, R. Andrew Moore, Sheena Derry, Jayne E. Edwards, and Henry J. McQuay, the results showed that while the results were not the most effective topical capsaicin can be used for those who do not respond to other treatments. The following method was used to reach this conclusion. Registered brands of capsaicin and chili pepper were used to create the topical treatment. This treatment was given to randomized adults who suffered from chronic pain due to neuropathic conditions such as diabetic neuropathy or post-herpetic neuralgia, or musculoskeletal disorders such as arthritis and back pain. Treatment included 0.075% capsaicin for participants with neuropathic conditions and 0.025% capsaicin for musculoskeletal conditions... half of the article... maintenance was also higher with capsaicin-treated subjects compared to those treated with placebo. A side effect of the pill was that subjects reported feeling a burning sensation in their stomach. However, this is a reasonable side effect to the benefit of burning more fuel (Lejeune, 2003). Each of these studies brought a positive result to prove that capsaicin is a useful thing to have in or on the body. Chili peppers have this capsaicin as a natural defense mechanism. However, it can reduce the pain of various types of chronic pain (Mason, 2004), be the best initial treatment for PHN (Hempenstall, 2005), be completely beneficial to the heart after exercise (Shin, 2004), and maintain weight reasonable body. loss ratio (Lejeune, 2003). Yes, there are side effects to using this treatment, such as burning near the applied area or in the stomach when it is digested, but the benefits outweigh the disadvantages.